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When is primaquine appropriate for antimalarial PPX

User Shalanda
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Final answer:

The primaquine appropriate for antimalarial PPX when preventing relapse in P. vivax and P. ovale malaria and killing the sexual stages of the parasite in P. falciparum malaria.

Step-by-step explanation:

Primaquine is an antimalarial drug that is appropriate for antimalarial prophylaxis and treatment in certain situations. Specifically, it is used for preventing relapse in P. vivax and P. ovale malaria, and for killing the sexual stages of the parasite in P. falciparum malaria. Primaquine is particularly important in malaria-endemic countries that are moving towards elimination.

However, it should be used with caution in individuals who are glucose-6-phosphate dehydrogenase (G6PD) deficient, as it can lead to serious adverse effects due to haemolytic toxicity. So therefore primaquine is appropriate for preventing relapse in P. vivax and P. ovale malaria and killing the sexual stages of the parasite in P. falciparum malaria. It is important in malaria-endemic countries moving towards elimination. Caution should be taken in individuals who are G6PD deficient.

User Ahmed Ashraf
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