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"In some cases of hyperlipidemia, LPL is defective. If a blood lipid profile is performed on patients with an LPL deficiency, which lipids would be elevated?"

User Noland
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Final answer:

In patients with lipoprotein lipase (LPL) deficiency, a blood lipid profile typically shows elevated levels of chylomicrons and VLDL, which correspond to increased triglycerides.

Step-by-step explanation:

Patients with a deficiency of lipoprotein lipase (LPL) often have a form of hyperlipoproteinemia known as type I, or familial hyperchylomicronemia.

LPL is crucial for the breakdown of chylomicrons and very low density lipoprotein (VLDL), both of which carry fatty acids and triglycerides. When LPL is defective, patients experience elevated levels of these lipoproteins.

Therefore, if a blood lipid profile is performed on patients with LPL deficiency, the lipids that would commonly be elevated are chylomicrons and very low density lipoprotein (VLDL), indicating heightened levels of triglycerides.

User Thierry Prost
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