Final answer:
A hypothesis test is conducted to determine if less than a certain percentage of subjects treated with a drug experience headaches. The alternative hypothesis suggests a decrease, thus a left-tailed test is appropriate for this situation.
Step-by-step explanation:
The question revolves around determining whether a specific drug treatment results in fewer headache incidents among treated subjects than a given percentage threshold, which requires a hypothesis test to answer.
If the claim is that less than a certain percentage of treated subjects experienced headaches, then the alternative hypothesis (Ha) would suggest the proportion is lower than the specified value. This would lead us to perform a left-tailed test because we are looking for evidence to support a decrease in the proportion (indicating a one-directional alternative).
Therefore, based on the information given, where the manufacturer's data indicated that 27 of the 261 treated subjects experienced headaches, one would conduct a left-tailed test. A left-tailed test is appropriate when the alternative hypothesis suggests that the parameter of interest is less than a particular value.
Since the clinical trial aims to prove the drug causes fewer headaches (which means less than a certain threshold), it aligns with the reasoning for a left-tailed hypothesis test.