The genes that are induced by tumor formation are MYC, EGFR and VEGFA.
The genes suppressed by tumor formation are TP53, CDKN2A and RB1.
Genes that exhibit a significant increase in expression during tumor formation are considered induced genes. These genes are likely to play a role in promoting tumor growth and progression.
MYC: A proto-oncogene that promotes cell proliferation and inhibits apoptosis. EGFR: A receptor tyrosine kinase that plays a role in cell growth, differentiation, and survival.
Genes that exhibit a significant decrease in expression during tumor Some of suppressed genes are TP53: A tumor suppressor gene that plays a critical role in cell cycle regulation and apoptosis.