Final Answer:
The given statement "A microarray is a slide with many DNA sequences spotted on it. To compare gene expression between two cell types, mRNA is isolated from each cell type. When mRNA is used to direct the synthesis of DNA, the resulting DNA is called complementary DNA (cDNA). cDNA from two cell types can be differentially labeled and applied to the microarray. DNA microarrays can be used to look for insertions or deletions if labeled DNA is utilized." is b) False
Step-by-step explanation:
DNA microarrays are primarily used to analyze gene expression levels, not for detecting insertions or deletions. They work by comparing the abundance of mRNA transcripts between two different cell types. mRNA isolated from each cell type is converted into complementary DNA (cDNA) and labeled with different dyes.
These labeled cDNAs are then hybridized to the microarray slide containing DNA sequences representing genes. The microarray detects the abundance of different mRNA transcripts in the two cell types based on the fluorescent signals from the labeled cDNAs.
This comparison helps identify genes that are upregulated or downregulated in one cell type compared to the other, providing insights into differences in gene expression.
Insertions or deletions in DNA sequences are typically analyzed using techniques like DNA sequencing or specific assays designed to detect structural variations within the DNA. Microarrays primarily focus on measuring gene expression and are not specifically designed to identify insertions or deletions in DNA sequences.
Therefore, while microarrays are powerful tools for studying gene expression, they are not used for directly detecting insertions or deletions in DNA.