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Cystic fibrosis is a homozygous recessive condition that affects 1 in 10,000 of the Hispanic population in the United States. Calculate the frequency of the dominant allele, the frequency of the recessive allele, and the percentage of heterozygous individuals (carriers) in the Hispanic population.

User Tushant
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Final answer:

The frequency of the dominant allele for cystic fibrosis is approximately 99,980,001/100,000,000. The frequency of the recessive allele is approximately 1/10,000. The percentage of heterozygous individuals (carriers) in the Hispanic population is approximately 2%.

Step-by-step explanation:

The frequency of the dominant allele (F) can be calculated using the Hardy-Weinberg formula, which is p^2 + 2pq, where p represents the frequency of the dominant allele. In this case, since cystic fibrosis is a homozygous recessive condition, the recessive allele (f) has a frequency of 1 in 10,000, so q = 1/10,000. To find p, we can subtract q from 1: p = 1 - q. Once we have p, we can calculate p^2 to get the frequency of the dominant allele. The percentage of heterozygous individuals (carriers) can be calculated using the formula 2pq, where p and q represent the frequencies of the dominant and recessive alleles, respectively.

Here's the step-by-step calculation:

p = 1 - 1/10,000 = 9,999/10,000

p^2 = (9,999/10,000)^2 = 99,980,001/100,000,000

The frequency of the dominant allele (F) is approximately 99,980,001/100,000,000.

q = 1/10,000 = 0.0001

2pq = 2 * (99,999/10,000) * 0.0001 = 0.019998 (approximately 2%)

User Ashikodi
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