Final answer:
Brugada syndrome is most often caused by a mutation in the SCN5A gene and is usually inherited in an autosomal dominant pattern, where only one mutated gene copy can cause the syndrome.
Step-by-step explanation:
Brugada Syndrome and Genetic Inheritance
Brugada syndrome is a genetic disorder that is most commonly attributed to a mutation in the SCN5A gene, which is influential in the function of heart muscle cells. This syndrome is typically inherited in an autosomal dominant pattern. This means that just one copy of the mutated gene, which is located on one of the 22 autosomal chromosomes, is sufficient to increase the risk of developing this condition. However, not all cases of Brugada syndrome are linked to the SCN5A gene, and not everyone with a mutation in this gene will develop the syndrome.
Autosomal recessive inheritance of genetic disorders is a pattern where the disorder corresponds to the recessive phenotype. An individual must inherit two copies of the mutated gene, one from each parent, to display symptoms of an autosomal recessive disorder, whereas heterozygous carriers do not show symptoms but can pass the trait to offspring. Common genetic disorders that follow an autosomal recessive pattern include cystic fibrosis and sickle cell anemia.