Question

The physician writes an order for amikacin 500 mg IV every 12 hr. The patient is 22 years old with mycobacterium avium complex in the lungs. The patient weighs 74 kg. The drug reference has the following information: What is the maximum safe dose that this patient can receive every 12 hours according to the drug literature? Enter the numeral only (not the unit) in your answer.

Answer 1

The maximum safe dose of amikacin every 12 hours cannot be determined without further specific dosing information from the drug literature, such as mg/kg recommendations or a maximum daily limit.

Step-by-step explanation:

To determine the maximum safe dose of amikacin that the patient can receive every 12 hours, we need additional information that isn't provided in the question such as the recommended dosage range for amikacin based on the patient's condition and weight (mg/kg), or a maximum daily limit. Without this specific information from the drug literature or drug reference guide, we can't calculate an accurate dose. In general, dosing for medications like amikacin is critical as it must balance efficacy against the risk of side effects and toxicity. It is especially important for drugs with serious side effects and those that are dosed based on patient body weight.