Answer:
The true statements regarding epigenetics are:
1. Epigenetic changes are transmissible from cell to cell.
2. Epigenetic changes may be transmitted to offspring.
3. Variations of gene expression that are unrelated to DNA sequence variants.
Epigenetic changes refer to modifications in gene expression patterns that do not involve changes in the DNA sequence itself. These changes can be heritable and passed on from cell to cell during cell division or from one generation to the next. They can influence gene expression without altering the underlying DNA sequence, leading to variations in gene expression that are unrelated to DNA sequence variants.