Final answer:
The first real cities were indeed in the region of Sumer in Mesopotamia, specifically in the city of Uruk.
Step-by-step explanation:
The statement that the first real cities were in the region of Sumer in Mesopotamia is True. Sumer was an ancient civilization that existed in southern Mesopotamia (modern-day Iraq) around 4000 to 2000 BCE. The city of Uruk, located in Sumer, is considered one of the oldest and earliest urban settlements in the world. It developed complex systems of government, economy, and architecture, establishing the foundation for future cities.
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