Final answer:
Maryland and Virginia
Step-by-step explanation:
The states that took the lead in the domestic slave trade when growing wheat became more popular to farm than tobacco were Maryland and Virginia. In the early 1800s, the demand for wheat increased, leading to a shift in agricultural practices. Maryland and Virginia, both located in the Chesapeake region, were known for their large populations of enslaved people who were forced to work on farms.
Learn more about Domestic slave trade and crop production