Final answer:
Dutch merchants and traders did not challenge Spanish domination of Asia, but instead focused on trade relations and alliances with local rulers.
Step-by-step explanation:
One of the statements that is NOT true about Dutch merchants and traders is that they challenged Spanish domination of Asia. While Dutch merchants and traders did become the center of European trade and commerce and formed the Dutch East India Company, they did not challenge Spanish domination of Asia. Instead, their focus was primarily on establishing trade relations and forming alliances with local rulers in various regions.
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