Final answer:
The mantle is the largest region of the Earth's interior.
Step-by-step explanation:
The largest region of the Earth's interior is the mantle. The mantle is located between the outer core and the Earth's crust. It is composed of solid rock that is semi-fluid and can flow very slowly over millions of years. The mantle makes up about 84% of the Earth's volume, making it the largest region of the Earth's interior.
Learn more about Earth's interior