Final answer:
Joseph McCarthy's 'Enemies' speech in Wheeling focused on accusing members of the U.S. government of communist infiltration.
Step-by-step explanation:
The main focus of Joseph McCarthy's 'Enemies' speech in Wheeling was to accuse members of the U.S. government, particularly the State Department, of communist infiltration. McCarthy claimed that communists were actively working to undermine the United States and its democracy. He used the speech to promote his anti-communist agenda and to advance his own political career.
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