Final answer:
In this excerpt from Hamlet, the word 'shrewdly' means 'sharply', describing the biting nature of the air.
Step-by-step explanation:
In this excerpt from William Shakespeare's play Hamlet, the word 'shrewdly' is used to describe the biting nature of the air. Based on the context, the best definition of 'shrewdly' in this context is 'sharply'. It signifies that the air is cold and biting, causing discomfort. This interpretation is supported by the use of the word 'nipping' in a subsequent line.
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