Final answer:
The major issue between the Mexican government and Texans in 1829 was the abolition of slavery by Mexico, which required Texans to free their slaves and imposed taxes on slaves to discourage slavery in Texas.
Step-by-step explanation:
The major issue that became between the Mexican government and Texans in 1829 was that Mexico abolished slavery and required Texans to emancipate their slaves. This decision was made to discourage slavery in Texas by charging taxes on slaves. It created tension and opposition from the Texans who heavily relied on slavery for their labor-intensive agricultural economy.
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