Final answer:
The gladiatorial games were the most remarkable event at the Coliseum, where trained fighters battled each other or dangerous animals. Over 400,000 people died in the Coliseum during these games.
Step-by-step explanation:
The most remarkable event to have taken place at the Coliseum was the gladiatorial games. These games were a popular form of entertainment in ancient Rome, where trained fighters known as gladiators would battle each other or dangerous animals in the arena. The Coliseum was specifically designed to host these games, and it is estimated that over 400,000 people died in the Coliseum during its time.
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