Final answer:
Columbus's discovery of the Americas had a negative impact on the native populations due to disease, crop death, and slave labor.
Step-by-step explanation:
The discovery of the Americas by Columbus had a significant impact on the native populations living there. One direct consequence was the introduction of diseases brought over by sailors. Many island crops were affected, leading to their death and a decline in food production. Additionally, the arrival of the Europeans resulted in the forced labor and enslavement of many indigenous peoples.
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