Final answer:
The best relative pronoun to complete the sentence is 'who.'
Step-by-step explanation:
In this sentence, the best relative pronoun to complete the sentence is who.
The sentence is providing information about Frances Folsom, who is the daughter of President Grover Cleveland's friend and law partner. Frances became the youngest first lady in U.S. history at the age of twenty-one.
Using the relative pronoun 'who' helps to connect the information about Frances Folsom as the subject of the sentence and emphasizes her role as the youngest first lady.
Learn more about Relative pronouns in English sentences