Final answer:
Alcohol is one of the most commonly abused central nervous system depressants due to its availability and cultural acceptance.
Step-by-step explanation:
Alcohol is one of the most commonly abused central nervous system depressants. It is a legal substance that can have significant effects on the brain and body when consumed in excessive amounts. Alcohol acts as a sedative, slowing down the activity of the central nervous system and depressing brain functions.
Other options in the list such as Xanax, Methadone, Valium, and Heroin are also depressants, but alcohol is the most widely abused depressant due to its availability and cultural acceptance.
Learn more about Commonly abused central nervous system depressants