Final answer:
The Mona Lisa is most famous for the subject's mysterious smile, highly-detailed and symbolic objects, and Leonardo da Vinci's realistic portrayal of the human body.
Step-by-step explanation:
Leonardo da Vinci's Mona Lisa is most famous for the subject's mysterious smile. The painting captivates viewers with the enigmatic expression on the subject's face, sparking endless speculation and interpretations. The highly-detailed and symbolic objects included in the painting, such as the landscape and the hands, further add to its allure. While the portrayal of the human body is realistic, it is not unflatteringly so; da Vinci masterfully captured the subtle nuance of the subject's form.
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