Final answer:
Calico cats have different colored fur due to the inactivation of one X chromosome, not an epistatic interaction.
Step-by-step explanation:
The statement that is false about calico cats is that the variation in coat color is an example of an epistatic interaction.
Calico cats are primarily females because the gene responsible for the calico pattern is located on the X chromosome. The different colored fur in calico cats is due to the inactivation of one of the X chromosomes in each cell during early development. This results in patches of different coat colors.
Epistatic interactions refer to the interaction between different genes that can modify or affect the expression of other genes. However, the coat color pattern in calico cats is primarily determined by X chromosome inactivation rather than an epistatic interaction.
Learn more about Calico cats