Final answer:
Living in the mountains of South America presented challenges such as harsh climate, limited agriculture, and isolation.
Step-by-step explanation:
One of the major challenges facing people who lived in the mountains of South America was the harsh climate and extreme conditions. The high altitude and steep terrain made it difficult for them to cultivate crops and sustain a reliable food source. Additionally, the isolation of mountainous regions made communication and trade with other communities more challenging.
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