Final answer:
The correct word to fill in the sentence is 'Tu.' It means 'your' in Spanish and is used to indicate that the person being addressed should give their hand.
Step-by-step explanation:
The correct word to fill in the given sentence is Tu. The sentence should read 'Me tienes que dar tu mano.'
'Tu' is the possessive pronoun in Spanish that means 'your.' In this case, it is used to indicate that the person being addressed should give their hand.
Other options given in the question like 'la' (the), 'mi' (my), and 'nuestra' (our) do not fit the context of the sentence.
Learn more about Spanish