Final answer:
The tragedy that resulted from the Indian Removal Act was the Trail of Tears.
Step-by-step explanation:
The tragedy that was a result of the Indian Removal Act was the Trail of Tears. The Indian Removal Act, signed into law by President Andrew Jackson in 1830, forced Native American tribes, primarily the Cherokee, to leave their ancestral lands and relocate to designated territories in present-day Oklahoma. The Trail of Tears refers to the forced and often deadly journey that thousands of Native Americans had to undertake, resulting in the loss of many lives.
Learn more about Indian Removal Act and the Trail of Tears