Final answer:
The correct answer is Sí, es vuestra madre.
Step-by-step explanation:
The correct answer to the question ¿Es María tu madre y la de tu hermana? is Sí, es vuestra madre. This response indicates that María is the mother of the person being addressed and their sister. The use of 'vuestra' implies that the speaker is referring to multiple people, such as addressing a group of siblings. The other options listed in the question are not grammatically correct.
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