Final answer:
The word Until does not work as an independent marker for this independent clause.
Step-by-step explanation:
The word Until does not work as an independent marker for this independent clause.
An independent marker is a word or phrase that connects independent clauses, indicating the relationship between them. However, the word Until does not convey a contrasting or continuing idea that would connect the independent clause 'my uncle was a fan of the team despite their many losses' to another independent clause.
On the other hand, the words Therefore, Regardless, and Nevertheless act as independent markers because they can be used to connect the independent clause with another independent clause, indicating a conclusion, contrast, or concession respectively.
Learn more about the use of independent markers in an independent clause