Final answer:
The appropriate direct object pronoun to fill in the blank is "la".
Step-by-step explanation:
The direct object pronoun that appropriately fills in the blank in the sentence is la.
The sentence translates to: "Pizza? No, I don't want to eat, thank you." The pronoun la is used as a direct object pronoun to refer to the pizza in the sentence.
Learn more about Direct object pronouns in Spanish