Answer:
Histones
Step-by-step explanation:
The spools from which DNA unwinds are made of proteins called histones. These histones play a crucial role in organizing and structuring DNA within the cell's nucleus. The DNA wraps around histone proteins to form nucleosomes, which are the fundamental units of chromatin. The coiling and packaging of DNA around histones not only facilitate the compaction of genetic material but also regulate access to the genetic information during processes such as transcription and replication.