Question

Which of these has occurred by the end of prophase?

The cell membrane has begun to pinch inward.
O The spindle is beginning to form.
The nuclear membrane has disappeared.
O Sister chromatids are separated.

Answer 1

By the end of prophase, the nuclear membrane disappears, the spindle begins to form, and sister chromatids start to separate.

Step-by-step explanation:

By the end of prophase, several changes have occurred in the cell. The nuclear membrane has disappeared, allowing the genetic material to become visible. Additionally, the spindle, which is a structure made up of microtubules, begins to form and helps separate the sister chromatids. However, the cell membrane has not started to pinch inward yet. This process occurs during cytokinesis, which comes after mitosis.

Learn more about Processes during mitosis