Final answer:
The disadvantage of the Colombian Exchange for Native Americans was the lack of immunity to European diseases, leading to deadly epidemics and societal upheaval.
Step-by-step explanation:
The disadvantage of the Colombian Exchange for Native Americans was that they didn't have natural immunities to European diseases like Smallpox. When the Europeans arrived in the Americas, they brought diseases that the Native Americans had never been exposed to before. Without immunity, the Native Americans suffered from devastating epidemics that decimated their populations.
This had a significant impact on Native American societies, as their populations were greatly reduced, which led to social upheaval and the loss of cultural practices. Additionally, the diseases weakened Native American communities, making them more vulnerable to European colonization.
In conclusion, the lack of immunity to European diseases was a major disadvantage of the Colombian Exchange for Native Americans, resulting in significant demographic and societal consequences.
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