Final answer:
Anabolic steroids can promote irreversible cardiovascular disease, diabetes, and decreased sexual desire.
Step-by-step explanation:
The supplement/drug that promotes irreversible cardiovascular disease, diabetes, and decreased sexual desire is anabolic steroids. Anabolic steroids are synthetic variations of the male hormone testosterone, and they can have numerous harmful effects on the body. Long-term abuse of anabolic steroids can lead to cardiovascular problems, such as increased risk of heart attacks and strokes. It can also contribute to the development of diabetes and disrupts hormonal balance, leading to decreased sexual desire and fertility.
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