Final answer:
In the immune system, co-stimulation between White Blood Cells (WBC’s), specifically T cells and B cells, requires an interaction between epitopes and immunocytokines. Epitopes are parts of an antigen recognized by the immune system, and immunocytokines are cytokines linked to an antibody which enhances the immune response.
Step-by-step explanation:
Co-stimulation between White Blood Cells (WBC’s) requires the interaction between epitopes and immunocytokines, so the answer is option 2. This process of co-stimulation occurs when WBC’s, specifically T cells and B cells, interact and communicate with each other to initiate and enhance an immune response. An epitope is a part of an antigen that is recognized by the immune system, specifically by antibodies or T-cell receptors, and immunocytokines are a subgroup of cytokines that were formed by the combination of a monoclonal antibody or an antibody fragment that has been connected to a cytokine.
For instance, when a T cell recognises an epitope on an antigen presented by a B cell, this interaction triggers the T cell to secrete immunocytokines. These immunocytokines then stimulate the B cell, enhancing its immune response, for example, by producing antibodies. Consequently, co-stimulation is a vital component of the immune response to infections and diseases.
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