Final answer:
Robert E. Lee surrendered to Ulysses S. Grant at the Appomattox Court House in Virginia on April 9, 1865, after being outnumbered and cut off by Grant's Union army.
Step-by-step explanation:
The site of Robert E. Lee's surrender to Ulysses S. Grant, after being cornered, was the Appomattox Court House in Virginia. This significant event in American history took place on April 9, 1865. Vastly outnumbered by Grant's Union army, Lee had to abandon Petersburg and Richmond with the aim of uniting his depleted force with Confederate forces commanded by General Johnston. However, Grant effectively cut him off, leading to Lee's surrender at Appomattox Court House, effectively signaling the end of the Civil War.
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