Final answer:
The slave trade most affected West Africa.
Step-by-step explanation:
The part of Africa that was most affected by the slave trade was West Africa. During the transatlantic slave trade, millions of Africans were captured and sold as slaves primarily from countries in West Africa such as Ghana, Nigeria, and Senegal. These enslaved Africans were transported to the Americas, particularly to regions such as the Caribbean and the southern United States.
Learn more about Slave trade in Africa