Final answer:
Potential side effects of leukotriene modifiers can range from relatively mild symptoms such as headache, nausea, and dizziness, to more serious complications such as an elevation in liver enzymes, vasculitis, or even Churg-Strauss Syndrome. Their proinflammatory response tends to be more potent and long-lasting compared to that of histamine. A broad understanding of these effects is crucial for NCLEX-RN Pharmacology.
Step-by-step explanation:
Leukotriene modifiers, used for treating allergic reactions, can have adverse effects. While leukotrienes in the body contribute to proinflammatory response in fighting off pathogens through induction of coughing, vomiting, and diarrhea, their modifiers can lead to unwanted side effects. These can include headache, nausea, dizziness, and sometimes rare but severe effects such as elevated liver enzymes, vasculitis, or Churg-Strauss Syndrome—an autoimmune condition. Notably, their effect is more potent and sustained compared to histamine's proinflammatory effects. Comprehension of this is vital in NCLEX-RN Pharmacology understanding and application.
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