Step-by-step explanation:
First-generation antipsychotics are dopamine receptor antagonists (DRA) and are known as typical antipsychotics.
The first-generation antipsychotics work by inhibiting dopaminergic neurotransmission; their effectiveness is best when they block about 72% of the D2 dopamine receptors in the brain. They also have noradrenergic, cholinergic, and histaminergic blocking action.