Answer:
Slavery had a significant impact on westward expansion in the United States. The issue of slavery was a major factor in the debates surrounding popular sovereignty, which allowed settlers in new territories to vote on whether or not to allow slavery. The Missouri Compromise of 1820, which established a line prohibiting slavery in certain territories, was another important event that reflected the nation's growing division over the issue of slavery. The Annexation of Texas, which was a slave state, further fueled tensions between the North and South. Finally, the Kansas-Nebraska Act of 1854, which repealed the Missouri Compromise and allowed for popular sovereignty in Kansas and Nebraska, led to violent clashes between pro-slavery and anti-slavery forces in the region. Overall, the issue of slavery played a central role in the westward expansion of the United States and was a major contributing factor to the outbreak of the Civil War.
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