Answer:
The details that best support the theme that loyalty to one's spouse is important are:
Brutus's statement praising Portia as his true and honorable wife and as dear to him as the ruddy drops that visit his sad heart.
Portia's insistence that she will not disclose Brutus's secrets and her willingness to prove her constancy by giving herself a voluntary wound in the thigh.
Therefore, options 2 and 3 best support the theme that loyalty to one's spouse is important