Final answer:
Calico cats are usually females because of the genetics of coat color inheritance in cats. However, in rare cases, male calico cats can exist, but they are usually sterile and have genetic abnormalities.
Step-by-step explanation:
Calico cats are usually females because of the genetics of coat color inheritance in cats. Coat color in cats is carried on the X chromosome. In female cats, one of the two X chromosomes is randomly inactivated in each cell during embryonic development, resulting in a tortoiseshell pattern if the cat has two different alleles for coat color. Male cats, having only one X chromosome, never exhibit a tortoiseshell coat color. However, in rare cases, male calico cats can exist, but they are usually sterile and have genetic abnormalities.