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List three reasons a TST would be contraindicated in a patient.

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A TST (Tuberculin Skin Test) is a diagnostic test used to detect the presence of tuberculosis (TB) infection. However, there are some situations where a TST would be contraindicated or not recommended. Here are three reasons why a TST may not be appropriate for a patient:

1. Prior positive TST: If a patient has already had a positive TST result in the past, then they are considered to have a latent TB infection and do not need another TST. Instead, a different test such as interferon-gamma release assay (IGRA) may be used to monitor the patient's TB infection status.

2. Recent vaccination: If a patient has received a bacille Calmette-Guérin (BCG) vaccine within the past 4-6 weeks, then the vaccine may cause a false-positive TST result. Therefore, it is recommended to wait at least 4-6 weeks after BCG vaccination before administering a TST.

3. Immunosuppression: If a patient is immunocompromised due to a medical condition or medication use, then the TST may not be reliable in detecting TB infection. In such cases, an IGRA test may be more appropriate, or other diagnostic tests may be necessary to evaluate the patient's TB infection status.

It is important to note that the decision to perform a TST or any diagnostic test is based on the patient's individual medical history and risk factors. Before administering any diagnostic test, healthcare providers should review the patient's medical history and assess any contraindications or potential risks associated with the test.
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