Answer:
When doing medical research with human subjects, four limitations that are unavoidable include:
Ethical considerations: Medical research involving human subjects is subject to strict ethical standards, including obtaining informed consent, ensuring the safety and welfare of the participants, and protecting their privacy and confidentiality. These ethical considerations can limit the types of studies that can be conducted and the ways in which they can be conducted.
Sample size: It may be difficult to obtain a large sample size of human subjects for a study, particularly for rare diseases or conditions. A small sample size can limit the generalizability of the study findings to the larger population.
Individual variability: Human subjects are inherently variable in their responses to treatments and interventions, due to factors such as age, sex, genetics, and environmental factors. This variability can make it difficult to draw generalizable conclusions from the study.
Time and cost: Medical research involving human subjects can be time-consuming and expensive, requiring significant resources for recruiting participants, conducting interventions, collecting and analyzing data, and ensuring the safety and welfare of the participants. This can limit the scope and duration of the study.
Step-by-step explanation: