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What is the effect of molecule size on a molecules ability to diffuse across a semipermeable membrane

User Carexcer
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The size of a molecule can significantly affect its ability to diffuse across a semipermeable membrane. Smaller molecules are generally able to diffuse more easily than larger molecules. This is because smaller molecules have less mass and can move more quickly, which allows them to pass through the tiny openings in the membrane more easily. In contrast, larger molecules are often too big to pass through the membrane and may require specialized transport mechanisms. Additionally, even if a larger molecule is able to pass through the membrane, it may do so more slowly due to its larger size and slower movement.

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