Answer: Fracture healing is one of the few postnatal procedures that is thought to be really regenerative since it recapitulates these ontological processes, returning the injured skeletal organ to its pre-injury cellular composition, structure, and biomechanical function.
It's interesting to note that around one-third of the mouse homologs of the genes produced by human embryonic stem cells are selectively activated, according to a comparison of the transcriptome of mouse callus tissues across a 21-day period of fracture healing.
Numerous homeotic genes that regulate the growth of appendicular limbs are also expressed more frequently when a fracture is mending.
6 Last but not least, fracture calluses exhibit all key morphogenetic pathways that are active during embryonic skeletal development6, and as a result, these pathways have been the focus of research to create new treatments.
Step-by-step explanation: