Step-by-step explanation:
The relationship between DNA and differentiation of a cell is that DNA is the blueprint that instructs a cell to differentiate into a specific type of cell. Differentiation is the process of a cell changing from its original state to become a more specialized cell type. During differentiation, DNA is read and the instructions it contains are used to create new proteins and modify existing proteins that are necessary for the cell to develop into its specialized form. DNA also contains instructions for controlling gene expression, which helps to direct the cell to differentiate into a specific cell type. Differentiation is a necessary process for a cell to take on a specialized role in the body, and DNA plays an important role in controlling the process.