Answer:
The organelles that make and package proteins are ribosomes and the endoplasmic reticulum (ER).
Ribosomes are small, spherical organelles that are found in the cytoplasm of cells. They are responsible for the synthesis of proteins, which they do by reading the genetic information in mRNA (messenger RNA) and using this information to assemble amino acids into polypeptide chains.
Once the polypeptide chains are synthesized by ribosomes, they are then transported to the endoplasmic reticulum (ER), which is a complex network of membranous tubes and sacs that is involved in the synthesis, modification, and transport of proteins and lipids. The rough endoplasmic reticulum (RER) is studded with ribosomes, and it is responsible for the synthesis and packaging of proteins. As the polypeptide chains are synthesized by ribosomes on the RER, they are folded and modified by a number of enzymes and other proteins that are located within the RER. Once the proteins are properly folded and modified, they are packaged into transport vesicles and transported to the Golgi apparatus for further processing and distribution to their final destination within the cell or outside of the cell.
Overall, ribosomes and the endoplasmic reticulum play important roles in the synthesis and packaging of proteins in cells.