Answer: A, C, and E
Generalized Lymphadenopathy indicates secondary syphilis which occurs 6 weeks - 6 months after the appearance of the chancre. Wartlike infectious lesions, also known as condylomata lata, may develop on the vulva, the perineum, or the anus. The presence of rash on the palms and soles also indicates secondary syphilis. Primary syphilis is a lesion that begins as a painless papule at the site of inoculation and becomes a nontender, shallow, indurated, and clean ulcer.