Interactions between the United States government and Native Americans have been complex and often fraught with tension. In the 18th and 19th centuries, American policy toward Native Americans changed drastically as a result of the American Revolution and the expansion of the nation.
Throughout this period, the US government sought to assimilate Native Americans into mainstream American society. This included a variety of different policies, ranging from the forced relocation of Native Americans to the establishment of boarding schools which sought to educate Native children in Euro-American customs and beliefs.
In addition, the government enacted a variety of regulations which sought to limit Native Americans' access to land, resources, and autonomy. These policies often included the establishment of reservations, the removal of Native Americans from their ancestral homelands, and the enforcement of laws which limited Native Americans' access to certain trade goods.
Ultimately, the government's attempts to assimilate Native Americans into mainstream American society were largely unsuccessful. Native Americans experienced a considerable decline in their population, with many tribes losing significant portions of their land and resources. Native Americans continue to struggle with poverty, health issues, and education, and continue to face discrimination in various aspects of American life.