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scientists studied nucleosome assembly following dna replication by using amino acids labeled with a heavy isotope. specifically, they grew cells for several generations in a medium that contained heavy amino acids so that all of the histone octamers contained heavy amino acids. then the cells were transferred to a medium that contained light amino acids, and the cells were allowed to complete one round of replication and nucleosome reassembly. histone octamers were then isolated and subjected to density-gradient centrifugation. which result would you expect if old octamers remained intact throughout the cell cycle and new octamers were assembled solely from newly synthesized histones?

User Quinz
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Geminin

Expression of a loss-of-function mutation in yeast causes cells and nuclei to enlarge and to accumulate DNA molecules to a level of 4n or higher. A gene encoding which of the following proteins is most likely affected by the mutation?

User Alan Dyke
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