The correct answer is B) Persia, the Fertile Crescent, and the eastern Mediterranean Sea.
Although you forgot to attach the map, we did some deep research to answer ypur question.
Once located a map of the time, we can say the following.
The statement that describes the location of the Persian Empire is "Persia, the Fertile Crescent, and the eastern Mediterranean Sea."
The Persian Empire had its center in what today is Iran.
We are talking about a place that developed from the Sumerian-Mesopotamian civilization, the oldest civilization known to man. The Sumerians settled in the middle of the Tigris and Euphrates Rivers and built impressive city-states such as Kish, Nippur, Eridu, Ur, Lagash, and Uruk.